Everton vs. Spurs (Saturday, 12.30pm)
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An Everton side who have dropped below a dreaded dotted line host a Tottenham Hotspur side who have climbed above a desired dotted line in Saturday's early Premier League kickoff at Goodison Park.
The Toffees are back in the drop zone owing to a goalless draw with Fulham in midweek, while the Lilywhites came from behind to overcome Brentford 3-2 in a tetchy London derby.
We say: Everton 1-3 Tottenham Hotspur
It was not for the want of trying at Craven Cottage, but there is seemingly no immediate solution to Everton's renewed attacking woes, although an extra day's rest and Tottenham's propensity to concede on the road offers Dyche's men a sliver of hope.
Postecoglou's crop fought fire with fire effectively on Wednesday evening, though, and while their defence may not emerge unscathed, their attacking forces should bail their rearguard out en route to a hoodoo-ending Goodison victory.
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> How Tottenham could line up against Everton
> Tottenham injury, suspension list vs. Everton
Brighton vs. Crystal Palace (Saturday, 3.00pm)
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Battered and bruised from a Kenilworth Road dismantling, Brighton & Hove Albion seek to right their midweek wrongs when Crystal Palace visit the Amex for the latest edition of the so-called M23 derby.
Roberto De Zerbi oversaw a humiliating 4-0 loss to Luton Town last time out, while Roy Hodgson's men made it back-to-back home wins with a 3-2 victory over basement boys Sheffield United.
We say: Brighton & Hove Albion 2-1 Crystal Palace
The result of Saturday's M23 derby may very well hinge on the respective fitness levels of Eze and Olise, but even if the duo are given the green light to line up, they cannot single-handedly solve Palace's perennial concerns at the back.
As chastening as Tuesday night was for Brighton, De Zerbi's men have developed a resilient streak at the Amex and should thrive under the pressure of making amends in front of their own fans, so we expect Saturday's crunch clash to go the way of the Seagulls.
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Burnley vs. Fulham (Saturday, 3.00pm)
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Both aiming to put a stop to miserable winless streaks, Burnley and Fulham clash at Turf Moor in Saturday's Premier League showdown.
The Clarets were put to the sword 3-1 by Manchester City in their midweek affair, while Marco Silva's men settled for a point in a goalless draw at home to Everton.
We say: Burnley 1-0 Fulham
With cup fatigue and fresh injury blows bedevilling a goal-shy Fulham side who have struggled to perform on the road all season, the stage could be set for a Burnley redemption tale at Turf Moor, especially when the Clarets' notable recent results against the visitors are taken into account.
Kompany's men will be working with a day's less rest than their capital counterparts and are hardly prolific themselves, but we still have faith in the Clarets to reignite their faltering survival charge by doing the double over the Cottagers.
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Newcastle vs. Luton (Saturday, 3.00pm)
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Having both hit the headlines with magnificent midweek victories, Newcastle United and Luton Town seek to prolong their respective feel-good factors in Saturday's Premier League encounter at St James' Park.
The Magpies knocked down the walls of the Villa Park fortress by beating Aston Villa 3-1 last time out, while the Hatters blew Brighton & Hove Albion to smithereens in a 4-0 battering.
We say: Newcastle United 2-1 Luton Town
Luton may have put Newcastle to the sword in December's emotionally-charged contest, and the Magpies' recent home exploits have left something to be desired, but do not be surprised to see Howe's men bring the Hatters crashing back down to earth.
Not since 1937 have Luton had a St James' Park win to shout about, and with Edwards's men still without the formula for defensive success on the road, even a Newcastle side without a recognised striker should come up trumps on home soil.
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Sheff Utd vs. Aston Villa (Saturday, 5.30pm)
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Two Premier Lague teams keen to quickly put aside midweek defeats do battle at Bramall Lane on Saturday, as basement club Sheffield United play host to top-four hopefuls Aston Villa.
While the Blades suffered a 3-2 defeat at Crystal Palace on Tuesday, Villa were beaten 3-1 at home against Newcastle United on the same evening.
We say: Sheffield United 1-2 Aston Villa
Every game is a must-win for Sheffield United and their dogged display in the reverse fixture with Aston Villa will provide them with confidence heading into their latest test at Bramall Lane, where they have accumulated eight of their 10 Premier League points this season.
However, Emery will be keen to see a response from his Villa side following their recent dip in form, and with a top-four finish still firmly in their sights, we can see a fired-up Lions outfit coming out on top in South Yorkshire.
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